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Roberto Gambari Selected Research

Thalassemia

3/2022Droplet Digital PCR for Non-Invasive Prenatal Detection of Fetal Single-Gene Point Mutations in Maternal Plasma.
3/2022Possible effects of sirolimus treatment on the long‑term efficacy of COVID‑19 vaccination in patients with β‑thalassemia: A theoretical perspective.
1/2022Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin).
12/2021Treatment of Erythroid Precursor Cells from β-Thalassemia Patients with Cinchona Alkaloids: Induction of Fetal Hemoglobin Production.
10/2020Discovery of Novel Fetal Hemoglobin Inducers through Small Chemical Library Screening.
11/2019Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia.
11/2019Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.
1/2018UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.
1/2018Consensus Predictive Model for Human K562 Cell Growth Inhibition through Enalos Cloud Platform.
11/2017BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression.
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Roberto Gambari Research Topics

Disease

57Neoplasms (Cancer)
05/2022 - 10/2002
41Cystic Fibrosis (Mucoviscidosis)
01/2022 - 01/2004
31Thalassemia
03/2022 - 01/2004
14Breast Neoplasms (Breast Cancer)
11/2014 - 10/2002
13Hepatocellular Carcinoma (Hepatoma)
10/2018 - 01/2005
12Infections
03/2022 - 06/2007
11Inflammation (Inflammations)
01/2022 - 01/2005
11Glioma (Gliomas)
08/2021 - 05/2014
11Sickle Cell Anemia (Hemoglobin S Disease)
10/2020 - 09/2003
11beta-Thalassemia (Cooley's Anemia)
04/2016 - 08/2003
8Leukemia
12/2015 - 09/2003
8BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2013 - 01/2009
7Glioblastoma (Glioblastoma Multiforme)
05/2022 - 08/2015
7Pneumonia (Pneumonitis)
01/2016 - 05/2007
7Carcinoma (Carcinomatosis)
01/2014 - 04/2006
6Inborn Genetic Diseases (Disease, Hereditary)
03/2022 - 12/2013
6Hemoglobinopathies
03/2022 - 11/2009
5Psoriasis (Pustulosis Palmaris et Plantaris)
01/2019 - 09/2003
4Colorectal Neoplasms (Colorectal Cancer)
08/2020 - 09/2004
4Neoplasm Metastasis (Metastasis)
01/2020 - 10/2002
4Skin Diseases (Skin Disease)
10/2009 - 09/2003
3COVID-19
12/2021 - 01/2021
3Cytokine Release Syndrome
12/2021 - 01/2021
3Bacterial Infections (Bacterial Infection)
01/2020 - 01/2012
3Melanoma (Melanoma, Malignant)
03/2018 - 01/2005
3Anemia
05/2016 - 11/2009
3Hematologic Diseases (Blood Diseases)
01/2015 - 02/2012
2Human Influenza (Influenza)
03/2022 - 08/2009
2Neuroblastoma
01/2021 - 05/2016
2Lung Diseases (Lung Disease)
10/2018 - 11/2016
2Pseudomonas Infections
10/2018 - 12/2010
2Hypoxia (Hypoxemia)
01/2018 - 12/2011
2Fibrosis (Cirrhosis)
01/2016 - 09/2008
2Acute Erythroblastic Leukemia (Erythroleukemia)
01/2015 - 10/2009

Drug/Important Bio-Agent (IBA)

32MicroRNAs (MicroRNA)IBA
05/2022 - 01/2009
26GlobinsIBA
01/2022 - 01/2008
23Fetal Hemoglobin (Hemoglobin F)IBA
01/2022 - 08/2003
23Interleukin-8 (Interleukin 8)IBA
07/2021 - 05/2007
21Proteins (Proteins, Gene)FDA Link
12/2021 - 09/2004
19Messenger RNA (mRNA)IBA
01/2022 - 08/2003
18DNA (Deoxyribonucleic Acid)IBA
10/2018 - 01/2003
17Pharmaceutical PreparationsIBA
01/2022 - 02/2003
15Hemoglobins (Hemoglobin)IBA
12/2021 - 11/2009
14Biological ProductsIBA
12/2021 - 06/2009
13Peptide Nucleic AcidsIBA
02/2022 - 01/2004
13CytokinesIBA
12/2021 - 05/2007
12ChemokinesIBA
12/2021 - 05/2007
10NF-kappa B (NF-kB)IBA
01/2021 - 10/2002
9Transcription Factors (Transcription Factor)IBA
10/2013 - 10/2002
7Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
01/2022 - 05/2007
6Interleukin-6 (Interleukin 6)IBA
07/2021 - 06/2007
6Temozolomide (Temodar)FDA LinkGeneric
11/2020 - 08/2015
5Furocoumarins (Furanocoumarins)IBA
12/2010 - 09/2003
4Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020 - 12/2009
4corilaginIBA
10/2018 - 12/2010
4AntioxidantsIBA
03/2018 - 02/2006
4Codon (Codons)IBA
01/2018 - 01/2008
4beta-Globins (beta Globin)IBA
05/2016 - 01/2004
4PlicamycinFDA Link
01/2015 - 08/2003
4Peptides (Polypeptides)IBA
10/2014 - 01/2012
4gamma-GlobinsIBA
10/2009 - 08/2003
4Photosensitizing Agents (Photosensitizers)IBA
10/2009 - 09/2003
4Estrogen Receptor alphaIBA
06/2007 - 10/2002
3RNA (Ribonucleic Acid)IBA
01/2021 - 01/2012
3Caspase 3 (Caspase-3)IBA
01/2021 - 12/2005
3SuspensionsIBA
11/2020 - 09/2010
3Doxorubicin (Adriamycin)FDA LinkGeneric
10/2018 - 05/2014
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2016 - 11/2006
3OligodeoxyribonucleotidesIBA
01/2015 - 12/2010
31-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA
10/2013 - 02/2003
35-MethoxypsoralenIBA
04/2011 - 11/2009
3OxidesIBA
11/2010 - 02/2006
2Sirolimus (Rapamycin)FDA Link
03/2022 - 01/2022
2sulforaphaneIBA
02/2022 - 01/2020
2ChloridesIBA
01/2022 - 05/2014
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2021 - 07/2021
2pyridineIBA
08/2021 - 04/2020
2Cell-Free Nucleic AcidsIBA
08/2020 - 10/2018
2TubulinIBA
04/2020 - 09/2008
2LigandsIBA
10/2019 - 10/2018
23- (4,5- dimethylthiazol- 2- yl)- 5- (3- carboxymethoxyphenyl)- 2- (4- sulfophenyl)- 2H- tetrazoliumIBA
10/2018 - 06/2007
2Biomarkers (Surrogate Marker)IBA
06/2018 - 01/2014
2Interleukin-17 (Interleukin 17)IBA
05/2018 - 01/2018
2beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA
01/2018 - 01/2016
2Adenosine (Adenocard)FDA LinkGeneric
01/2018 - 09/2004
2angelicinIBA
01/2017 - 09/2003
2InterleukinsIBA
01/2017 - 03/2011
2EnzymesIBA
12/2016 - 11/2006
2MethyltransferasesIBA
05/2016 - 08/2015
2AntagomirsIBA
05/2016 - 03/2016
2IronIBA
05/2016 - 06/2007
2Hormones (Hormone)IBA
01/2015 - 10/2002
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2015 - 12/2012
2Cisplatin (Platino)FDA LinkGeneric
05/2014 - 09/2003

Therapy/Procedure

36Therapeutics
05/2022 - 05/2003
4Precision Medicine
01/2022 - 01/2019
3Drug Therapy (Chemotherapy)
05/2016 - 01/2015
2Investigational Therapies (Experimental Therapy)
11/2019 - 04/2012
2Traditional Medicine (Folk Remedies)
01/2017 - 01/2008
2Blood Transfusion (Blood Transfusions)
05/2016 - 11/2009